Antibiotic lock therapy: a therapeutic option worth considering. Bibliographic revision.
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Keywords

Central venous catheter, antibiotic lock therapy, biofilm.

Abstract

Catheter-related infections are a significant complication that increase morbility, mortality and resource consumption.  The treatment of choice is catheter removal and administration of systemic antibiotic therapy. For long-term venous catheters, antibiotic lock therapy (ALT)  may be considered. In this review, we focus on long-term central venous catheter CVS and peripherally inserted CVS. Combined with systemic antibiotic therapy, it has achieved a high cure rate in the types of infections. With appropriate case selection, the catheter salvage rate is 80%, depending on the type of patogen and the symptoms of the infection.

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