Gastrointestinal bleeding related to Kaposi’s Sarcoma is rare in AIDS patients; the etiology of anemia is usually multifactorial.
We describe the case of a HIV infected, 53 year old patient with refractory anemia requiring frequent transfusion support. He was a patient with multiple complications and recent introduction of drugs that could justify myelosuppression and anemia. Due to inconclusive endoscopic examinations, the appearance of melena was the clue of the investigation, which concluded in the diagnosis of duodenal Kaposi’s Sarcoma.
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